Antagonists appearing in animated films and series. This may include antagonists who originally appeared in comic books or live action films that were adapted into animation, such as Thanos, Green Goblin, and Stay Puft Marshmellow Man.
EXTREMELY IMPORTANT: Do not add Anime characters under this category. Those belong only in the subcategory, Anime Villains.
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A
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- Aardvark (Ice Age)
- Abel Cuvier
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- Abracadaver
- Abrasive Sponge
- Ace (Thomas & Friends)
- Acheron
- Acid Storm
- Adam (Hazbin Hotel)
- Admiral Rampart
- Admiral Trench
- Adrian Graye Vernworth
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- Agent (Animator vs. Animation)
- Aggie (The Loud House)
- Aggie Prenderghast
- Aiwei
- Akumatized villains
- Al McWhiggin
- Al-G Rhythm
- Alador Blight
- Alameda Slim
- Alaskan Bull Worm
- Alastor (Hazbin Hotel)
- Albert
- Albert (Family Guy)
- Albert (Johnny Test)
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- Alexander Hugo
- Alexis Luthor
- Alfredo (The Casagrandes)
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- Ali (VeggieTales)
- Ali Blobi
- Alien Rice Weevils
- Aliens (Chicken Little)
- Aliens (Katy Meets the Aliens)
- Aliens (The Loud House)
- Allan
- Alley Dogs
- Alligators (The Loud House)
- Allomere
- Almighty Tallest
- Almighty Tallests
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- Aloysius O'Hare
- Alternate Reality Chester and AJ
- Alternate Reality Mr. Krabs
- Alternate Reality Mr. Turner
- Alternate timeline Benjamin Krupp
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- Amanda Killman
- Amazing Rope Guy
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- Ammonites
- Amoeba Boys
- Amon
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- Anagan
- Anais Watterson
- Anansi
- Ancestral Witches
- Anderson, Taylor and Pablo
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- Andrealphus
- Andrew Hawkman
- Andy Bangs
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- Angelica Pickles
- Angelica Sin
- Anglerfish
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- Angry Alien
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- Angry Penguin
- Animaestro
- Animal Control (The Secret Life of Pets)
- Animan
- Animatronic Hieronymus Glove
- Ant-One
- Anthony DeMartino
- Anthony Trumper
- Anti-Cosmo
- Anti-Fairies
- Anti-Fairy Council
- Anti-Jorgen
- Anti-Sparky
- Anti-Wanda
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- Anton Ego
- Antonio Perez
- Anxiety
- Apes (The Fairly OddParents)
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- Archie
- Archie (The Penguins of Madagascar)
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- Aresia
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- Aristides Silk
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- Armagedroid
- Armando and Tipa
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- Armzo
- Art Appraiser
- Artemio Alcaraz
- Arthur (Wreck-It Ralph)
- Asajj Ventress
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- Atomic Flounder
- Attack Dog with Built-in-force-field
- Aunt Sarah
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- Axxin/Engineer
- Ay
- Azrael (The Smurfs Film Series)
- Azula
- Azulon
B
- B2 super battle droid
- Baatar Jr.
- Baby Bot
- Baby Eddie
- Baby Pumpkins
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- Backwarder
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- Bad Guys United
- Bad Piggies
- Bad Po
- Baddie Bots
- Bakerix
- Balthazar (Rango)
- Balthazar Bratt
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- Banana Boom-Boom
- Banana Trees
- Bandits (VeggieTales)
- Bane (DC)
- Baraka
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- Baron
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- Baron von Cavitus
- Baron von Cavitus' Minions
- Barracuda (Finding Nemo)
- Barry (The Penguins of Madagascar)
- Bartleby Farnum
- Baryonyxes
- BASA Guards
- Bats (Where's Waldo?)
- Battle Droids
- Baxter (Back at the Barnyard)
- Baz and Bernie
- Beagle Boys
- Bear (Balto)
- Bear (Horseland)
- Bear (The Fox and the Hound)
- Bear (The Loud House)
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- Beautiful Gorgeous
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- Beavis and Butt-head
- Becky (The Casagrandes)
- Bees (Disney)
- Bees (The Loud House)
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- Befana
- Bela
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- Belly Dragger
- Belly Draggers (The Amazing Threehorn Girl)
- Belmod
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- Ben Haramed (VeggieTales)
- Bendy (Foster's Home for Imaginary Friends)
- Beppi The Clown
- Bernie Lumen
- Berry
- Berry the Ice Monster
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- Beth (Polly Pocket)
- Beth (Total Drama)
- Bian Zao
- Big Baby (Toy Story)
- Big Bad Hippo