Mistress (Revenge Room)

Mistress (ミストレス) is the primary antagonist of the 2014 PC visual novel game "Revenge Room ~Jutai o Kyouyou Sareru Chikashitsu~" (リベンジルーム ～受胎を強要される地下室～) by developer Lune. Though unnamed in the game, she is almost assuredly the sinister Dr. Shizuka Ichijou from the game "Jutaijima", due to her virtually identical appearance.