Nephilia (Spider-Man Cartoon 1981)

Nephilia: A scientist named Dr. Bradley Shaw and his assistant Penny plotted to attain Spider-Man's blood and a DNA sample of a nephilia spider into order to duplicate his powers use them for Bradley's own needs. Unfortunately, he ends up becoming Nephilia: a mutant with a man's torso and a spider body from the waist down. When Penny ends up betraying Nephilia by cutting the boxcar containing gold loose, Nephilia helps Spider-Man into stoppong the runaway boxcar. After Penny was stopped, Spider-Man restored Nephilia back to Dr. Bradley Shaw.